169 lines
7.5 KiB
Python
169 lines
7.5 KiB
Python
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#!/usr/bin/env python3
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# -*- coding: utf-8 -*-
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import re
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print("修复health_11的结构...")
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# 读取文件
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with open('/Users/apple/Documents/cursor/教务系统/frontend_大健康/src/mocks/resumeInterviewMock.js', 'r', encoding='utf-8') as f:
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content = f.read()
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# 备份
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with open('/Users/apple/Documents/cursor/教务系统/frontend_大健康/src/mocks/resumeInterviewMock.js.backup_health11_fix', 'w', encoding='utf-8') as f:
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f.write(content)
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# 找到health_11的开始和结束
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health11_start = content.find('"id": "health_11"')
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if health11_start == -1:
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print("未找到health_11")
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exit(1)
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# 找到industries数组结束
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industries_end = content.find('];', health11_start)
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# 获取health_11的内容
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health11_content = content[health11_start:industries_end]
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# 移除所有错误位置的questions
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# 1. 找到所有positions
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positions_matches = list(re.finditer(r'"id":\s*"health_11_\d+"', health11_content))
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# 提取所有position对象
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positions = []
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for i, match in enumerate(positions_matches):
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start = match.start()
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# 找到这个position的结束（下一个position的开始或positions数组结束）
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if i < len(positions_matches) - 1:
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end = positions_matches[i + 1].start()
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else:
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# 最后一个position，找到它的结束
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# 查找requirements数组结束后的'}'
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req_end = health11_content.find('"requirements":', start)
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if req_end > 0:
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# 找到requirements数组的结束
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bracket_start = health11_content.find('[', req_end)
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bracket_end = health11_content.find(']', bracket_start)
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# position对象的结束是']'后的'}'
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pos_end = health11_content.find('}', bracket_end)
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end = pos_end + 1
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else:
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end = len(health11_content)
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position_obj = health11_content[start:end]
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# 移除position内的questions（如果有）
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if '"questions":' in position_obj:
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# 找到requirements的结束
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req_end_match = re.search(r'"requirements":\s*\[[^\]]*?\]', position_obj)
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if req_end_match:
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# 保留到requirements结束
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clean_position = position_obj[:req_end_match.end()]
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# 查找position对象原本的结束'}'
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remaining = position_obj[req_end_match.end():]
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# 跳过questions内容，找到属于position的'}'
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# 这需要计算括号平衡
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clean_position += '\n }'
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else:
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clean_position = position_obj
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else:
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clean_position = position_obj
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positions.append(clean_position)
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# 重建health_11对象
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health11_new = ''' {
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"id": "health_11",
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"name": "药物研发",
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"positions": [
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'''
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# 添加所有positions
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health11_new += ',\n '.join(positions)
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# 关闭positions数组
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health11_new += '''
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],
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"questions": [
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{
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"id": "group_q1",
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"question": "二、生物制药特性",
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"subQuestions": [
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{
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"id": "q1",
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"question": "生物药物有哪些化学与生物学特性？",
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"answer": "生物药物的化学本质可以是蛋白质、多肽、抗体或核酸，分子量大多在数万到数十万之间。它们的稳定性受温度、湿度、光照影响，需要在冷链或特定环境下保存；溶解性与分子量、荷电状态相关；药代动力学则取决于分子大小与代谢通路。"
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},
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{
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"id": "q2",
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"question": "体液调控药物有哪些作用？",
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"answer": "体液调控药物包括胰岛素（调控血糖）、血液制品（如白蛋白、免疫球蛋白）、促红细胞生成素（刺激红细胞生成）和脂肪因子（调节脂质代谢）。这些药物通过补充或调节人体内源性活性物质，实现代谢平衡、免疫增强和生理调控。"
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},
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{
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"id": "q3",
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"question": "生物制药中的主要产品有哪些？",
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"answer": "生物制药主要产品包括：治疗性蛋白（如胰岛素、生长激素）；单克隆抗体（如抗肿瘤药物）；疫苗（如重组疫苗）；血液制品（如凝血因子）；细胞与基因治疗产品（如CAR-T）。这些产品广泛应用于肿瘤、免疫、代谢疾病治疗。"
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}
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]
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},
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{
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"id": "group_q2",
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"question": "三、药理学特性",
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"subQuestions": [
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{
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"id": "q4",
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"question": "生物制药的药理学特性是什么？",
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"answer": "生物制药的药理学特性包括：高特异性（作用于特定靶点或受体）；低毒性（较少产生非特异性反应）；免疫原性（可能引起抗药抗体）；药代动力学复杂（代谢途径多样化）；给药途径受限（多为注射给药）。理解这些特性对药物研发至关重要。"
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},
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{
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"id": "q5",
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"question": "生物药物的清除途径有哪些？",
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"answer": "生物药物主要通过以下途径清除：肾脏滤过（小分子蛋白）；肝脏代谢（酶解作用）；网状内皮系统吞噬（大分子药物）；受体介导的内吞（抗体类）；蛋白酶降解（多肽类）。不同药物的清除机制影响其半衰期和给药频率设计。"
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},
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{
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"id": "q6",
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"question": "如何评价生物药物的安全性？",
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"answer": "生物药物安全性评价包括：免疫原性测试（抗药抗体检测）；毒理学研究（急性、慢性毒性）；生殖毒性评估；致癌性试验；过敏反应监测；细胞因子释放综合征评估。这些评价需遵循ICH等国际指南，确保临床应用安全。"
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}
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]
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},
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{
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"id": "group_q3",
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"question": "四、生物药物分类",
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"subQuestions": [
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{
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"id": "q7",
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"question": "常见的生物药物类型有哪些？",
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"answer": "常见生物药物包括：重组蛋白药物（如干扰素、EPO）；单克隆抗体（如贝伐珠单抗）；融合蛋白（如依那西普）；多肽激素（如GLP-1类似物）；疫苗（如HPV疫苗）；基因治疗药物；细胞治疗产品。每类药物都有独特的作用机制和临床应用。"
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},
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{
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"id": "q8",
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"question": "抗体药物的作用机制有哪些？",
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"answer": "抗体药物作用机制包括：直接中和（阻断配体-受体结合）；ADCC效应（抗体依赖的细胞毒性）；CDC效应（补体依赖的细胞毒性）；信号传导阻断；免疫检查点抑制；药物偶联递送。这些机制使抗体药物在肿瘤、自身免疫疾病治疗中发挥重要作用。"
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},
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{
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"id": "q9",
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"question": "核酸类药物的发展现状如何？",
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"answer": "核酸药物包括DNA和RNA类，已在疫苗（如mRNA新冠疫苗）、基因治疗（CRISPR相关药物）中广泛应用。虽然在稳定性、递送效率方面仍存在挑战，但发展前景广阔。"
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}
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]
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}
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]
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}'''
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# 替换原内容
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content_before = content[:health11_start]
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content_after = content[industries_end:]
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# 查找health_10的结束
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health10_end = content_before.rfind('},')
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# 构建新内容
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new_content = content_before[:health10_end + 2] + '\n' + health11_new + '\n' + content_after
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# 写回文件
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with open('/Users/apple/Documents/cursor/教务系统/frontend_大健康/src/mocks/resumeInterviewMock.js', 'w', encoding='utf-8') as f:
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f.write(new_content)
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print("✓ 修复完成！")
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